Mass spectrometry is the analysis techniques, ionization the sample nto a gaseous mixture of ion, and separation according to the load ratio (m/z)./p> , Mass spectrometer is composed of the following sections. Ion source is the devices cause the atoms or molecules of analysis samples into charged particles (ions), and to accelerate the ions into the analyzer, according to the different methods of ionization, biomacromolecule analysis commonly used are electrospray Ionization and matrix Assisted Laser Desorption.

According to the quality analyzer, the following several kinds are common quadrupole mass spectrometer (Q), the ion TRAP mass spectrometer (Ions TRAP), the time of flight mass spectrometer (TOF), fourier transform ion cyclotron resonance mass spectrometer (FT - ICRMS).